Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 18/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281243 | 1.00 | TGFBR1 (0.72) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281220 | 0.90 | TGFBR1 (0.71) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30855625 | 0.90 | TGFBR1 (0.71) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30855660 | 0.88 | TGFBR1 (0.61) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281212 | 0.88 | TGFBR1 (0.61) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281227 | 0.86 | TGFBR1 (0.72) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281257 | 0.86 | TGFBR1 (0.71) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281269 | 0.85 | TGFBR1 (0.64) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281253 | 0.84 | TGFBR1 (1.00) | TGFBR1CYP1A2 | |
| SCHEMBL30855624 | 0.84 | TGFBR1 (1.00) | TGFBR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384511-A1 | FUSED RING HETEROARYL COMPOUNDS AND USE THEREOF | Bisichem Co., Ltd. (KR) | 2024-06-19 | — | — | EP | disclosed |
| CN-117881669-A | Condensed ring heteroaryl compounds and uses thereof | 比西切姆有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023018313-A1 | FUSED RING HETEROARYL COMPOUNDS AND USE THEREOF | BISICHEM CO., LTD. (KR) | 2023-02-16 | — | — | WO | disclosed |