SCHEMBL30183017

SCHEMBL30183017

CCCOCc1cc(NC2CCOCC2)c2[nH]c(-c3ccccc3)cc2c1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 6/20 0.41
KIT P10721 1/20 0.36
FLT3 P36888 1/20 0.36
CARM1 Q86X55 6/20 0.34
NPY5R Q15761 4/20 0.34
BRD4 O60885 2/20 0.33
SOAT1 P35610 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31022421 0.98 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R
SCHEMBL31022339 0.93 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R
SCHEMBL30224970 0.93 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R
SCHEMBL30182940 0.92 CSF1R (0.42) CSF1RKITFLT3CARM1NPY5R
SCHEMBL30224759 0.91 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R
SCHEMBL31022532 0.91 CSF1R (0.41) CSF1RKITFLT3CARM1NPY5R
SCHEMBL31022188 0.91 CSF1R (0.39) CSF1RKITFLT3CARM1NPY5R
SCHEMBL24988874 0.91 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R
SCHEMBL30224873 0.91 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R
SCHEMBL30224124 0.91 CSF1R (0.40) CSF1RKITFLT3CARM1NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023013996-A1 INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-02-09 WO disclosed