SCHEMBL31022339

SCHEMBL31022339

CCOCCOCc1cc(NC2CCOCC2)c2[nH]c(-c3ccccc3)cc2c1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 6/20 0.40
NPY5R Q15761 4/20 0.39
KIT P10721 1/20 0.38
FLT3 P36888 1/20 0.38
CARM1 Q86X55 6/20 0.36
P2RY12 Q9H244 1/20 0.32
BRD4 O60885 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30224970 1.00 CSF1R (0.40) CSF1RNPY5RKITFLT3CARM1
SCHEMBL30182940 0.95 CSF1R (0.42) CSF1RNPY5RKITFLT3CARM1
SCHEMBL31022421 0.94 CSF1R (0.40) CSF1RNPY5RKITFLT3CARM1
SCHEMBL30183017 0.93 CSF1R (0.41) CSF1RNPY5RKITFLT3CARM1
SCHEMBL30224759 0.93 CSF1R (0.40) CSF1RNPY5RKITFLT3CARM1
SCHEMBL30224873 0.92 CSF1R (0.40) CSF1RNPY5RKITFLT3CARM1
SCHEMBL27237572 0.92 CSF1R (0.40) CSF1RNPY5RKITFLT3CARM1
SCHEMBL29185241 0.91 NPY5R (0.41) NPY5R
SCHEMBL30224934 0.91 NPY5R (0.41) NPY5R
SCHEMBL29205646 0.91 NPY5R (0.41) CSF1RNPY5RCARM1P2RY12BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024158205-A1 INDOLE DERIVATIVE WITH SUBSTITUENT AND PHARMACEUTICAL USE 주식회사 미토이뮨테라퓨틱스 2024-08-02 WO claimed
WO-2024158205-A1 INDOLE DERIVATIVE WITH SUBSTITUENT AND PHARMACEUTICAL USE 주식회사 미토이뮨테라퓨틱스 2024-08-02 WO disclosed