Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649285 | 1.00 | ATR (0.36) | ATRL3MBTL3L3MBTL1GSK3BDYRK1A | |
| SCHEMBL30183298 | 0.89 | L3MBTL1 (0.39) | ATRL3MBTL3L3MBTL1GSK3BDYRK1A | |
| SCHEMBL20649068 | 0.89 | L3MBTL1 (0.39) | ATRL3MBTL3L3MBTL1GSK3BDYRK1A | |
| SCHEMBL20649295 | 0.88 | F2 (0.34) | ATRGSK3BDYRK1AHRH3 | |
| SCHEMBL30183461 | 0.88 | F2 (0.34) | ATRGSK3BDYRK1AHRH3 | |
| SCHEMBL20649200 | 0.88 | TRPC3 (0.36) | ATRL3MBTL3L3MBTL1LRRK2SMYD2 | |
| SCHEMBL30183301 | 0.88 | TRPC3 (0.36) | ATRL3MBTL3L3MBTL1LRRK2SMYD2 | |
| SCHEMBL20649153 | 0.86 | LRRK2 (0.39) | ATRL3MBTL3L3MBTL1LRRK2SMYD2 | |
| SCHEMBL30183348 | 0.86 | LRRK2 (0.39) | ATRL3MBTL3L3MBTL1LRRK2SMYD2 | |
| SCHEMBL20649115 | 0.86 | ATR (0.49) | ATRL3MBTL3L3MBTL1LRRK2MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | claimed |
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | disclosed |