Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.69 |
| ▸ | HTR1A | P08908 | 5/20 | 0.66 |
| ▸ | HTR6 | P50406 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 4/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND1 | P24385 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017882 | 0.89 | HTR1A (0.72) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL1118996 | 0.84 | HTR2A (0.88) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL23042909 | 0.83 | HTR2A (0.71) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL14950623 | 0.83 | HTR1A (0.76) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL6933897 | 0.82 | HTR2A (0.70) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL22027268 | 0.82 | HTR2A (1.00) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| Iodide SCHEMBL30366641 | 0.82 | HTR2A (0.69) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL91128 | 0.80 | HTR2A (0.72) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL29414676 | 0.80 | HTR2A (0.72) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| Diethyltryptamine SCHEMBL517713 | 0.80 | HTR1A (1.00) | HTR2AHTR1AHTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283386-A2 | SAFER PSYCHOACTIVE COMPOSITIONS | ARCADIA MEDICINE, INC. (US) | 2023-01-12 | — | — | WO | disclosed |