SCHEMBL30183069

[2H]C([2H])([2H])n1ncc2cc(-c3nc(NCc4cccc(F)c4)[nH]c3-c3cccc(C)n3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	TGFBR1	P36897	19/20	1.00

▸	CYP1A2	P05177	3/20	0.78

▸	CYP2D6	P10635	2/20	0.67

▸	CYP2C9	P11712	2/20	0.67

▸	CYP2C19	P33261	2/20	0.67

▸	MAPK14	Q16539	5/20	0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29281234	0.94	TGFBR1 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30855655	0.94	TGFBR1 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30855658	0.88	TGFBR1 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30183107	0.88	TGFBR1 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL29281226	0.86	TGFBR1 (1.00)	TGFBR1CYP1A2MAPK14
SCHEMBL29281260	0.85	CYP1A2 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30855650	0.85	CYP1A2 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30855661	0.85	TGFBR1 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL29281246	0.85	TGFBR1 (1.00)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL29281208	0.84	TGFBR1 (0.89)	TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4384511-A1	FUSED RING HETEROARYL COMPOUNDS AND USE THEREOF	Bisichem Co., Ltd. (KR)	2024-06-19	—	—	EP	disclosed
WO-2023018313-A1	FUSED RING HETEROARYL COMPOUNDS AND USE THEREOF	BISICHEM CO., LTD. (KR)	2023-02-16	—	—	WO	disclosed