Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 5/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.37 |
| ▸ | TTK | P33981 | 5/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123484 | 1.00 | PTK2 (0.38) | PTK2PTK6TTKJAK2JAK1 | |
| Formic Acid SCHEMBL30171801 | 0.98 | PTK2 (0.36) | PTK2PTK6TTKJAK2JAK1 | |
| SCHEMBL30385433 | 0.93 | PTK2 (0.42) | PTK2PTK6TTKJAK2JAK1 | |
| SCHEMBL24871015 | 0.93 | PTK2 (0.41) | PTK2PTK6TTKCNR2AURKB | |
| Hydrochloric Acid SCHEMBL25173468 | 0.92 | PTK2 (0.41) | PTK2PTK6TTKJAK2JAK1 | |
| SCHEMBL22123091 | 0.92 | PTK6 (0.35) | PTK2PTK6TTK | |
| SCHEMBL22122896 | 0.91 | PTK2 (0.35) | PTK2PTK6TTKJAK2JAK1 | |
| Formic Acid SCHEMBL30171526 | 0.91 | PTK2 (0.40) | PTK2PTK6TTKCNR2AURKB | |
| Formic Acid SCHEMBL30171731 | 0.90 | PTK6 (0.34) | PTK2PTK6TTK | |
| SCHEMBL24112441 | 0.90 | PTK2 (0.36) | PTK2PTK6TTKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | claimed |