Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.37 |
| ▸ | TTK | P33981 | 3/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123294 | 0.94 | PTK2 (0.43) | PTK2PTK6TTKHTR4AURKB | |
| SCHEMBL22122856 | 0.94 | PTK2 (0.43) | PTK2PTK6TTKHTR4AURKB | |
| SCHEMBL22122871 | 0.94 | PTK2 (0.39) | PTK2PTK6TTKHTR4AURKB | |
| Hydrochloric Acid SCHEMBL30172045 | 0.93 | PTK2 (0.43) | PTK2PTK6TTKHTR4AURKB | |
| Hydrochloric Acid SCHEMBL30171580 | 0.93 | PTK2 (0.43) | PTK2PTK6TTKHTR4AURKB | |
| SCHEMBL22123484 | 0.93 | PTK2 (0.38) | PTK2PTK6TTKHTR4AURKB | |
| SCHEMBL30183114 | 0.93 | PTK2 (0.38) | PTK2PTK6TTKHTR4AURKB | |
| SCHEMBL22123264 | 0.93 | PTK2 (0.46) | PTK2PTK6TTKHTR4AURKB | |
| SCHEMBL22122896 | 0.91 | PTK2 (0.35) | PTK2PTK6TTKJAK2JAK1 | |
| Formic Acid SCHEMBL30171801 | 0.91 | PTK2 (0.36) | PTK2PTK6TTKHTR4AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |