Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 7/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123797 | 0.97 | PTK6 (0.45) | TTKPTK6AURKBMAPKAPK5QPCT | |
| SCHEMBL22122944 | 0.96 | PTK6 (0.47) | TTKPTK6AURKBMAPKAPK5CD274 | |
| SCHEMBL22124775 | 0.94 | PTK6 (0.45) | TTKPTK6AURKBMAPKAPK5QPCT | |
| SCHEMBL22122828 | 0.92 | TTK (0.44) | TTKPTK6MAPKAPK5CD274KDM4E | |
| SCHEMBL30171757 | 0.92 | TTK (0.44) | TTKPTK6MAPKAPK5CD274KDM4E | |
| SCHEMBL22142812 | 0.92 | TTK (0.43) | TTKPTK6AURKBMAPKAPK5CD274 | |
| SCHEMBL22123500 | 0.91 | MAPKAPK5 (0.49) | TTKMAPKAPK5CD274 | |
| SCHEMBL22122922 | 0.90 | PTK6 (0.43) | TTKPTK6AURKBQPCTKDM4E | |
| SCHEMBL30171553 | 0.90 | PTK6 (0.43) | TTKPTK6AURKBQPCTKDM4E | |
| SCHEMBL22124457 | 0.90 | TTK (0.42) | TTKPTK6AURKBMAPKAPK5CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | claimed |