Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HTR6 | P50406 | 12/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CPT1A | P50416 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901412 | 1.00 | KMT2A (0.57) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL30183477 | 0.80 | HTR6 (0.58) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL217077 | 0.80 | HTR6 (0.58) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL220450 | 0.74 | HTR6 (0.62) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL30159067 | 0.74 | HTR6 (0.62) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL30986327 | 0.74 | HTR6 (0.63) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL2254734 | 0.73 | HTR6 (0.47) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL28855969 | 0.71 | HTR6 (0.58) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL2254417 | 0.71 | MEN1 (0.64) | KMT2AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL29678455 | 0.71 | HTR6 (0.58) | KMT2AHTR6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300956-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZOL DERIVATIVES FOR USE IN THERAPY | SANOFI (FR) | 2024-09-12 | — | — | US | disclosed |
| EP-4370518-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZOL DERIVATIVES FOR USE IN THERAPY | Sanofi (FR) | 2024-05-22 | — | — | EP | disclosed |
| CN-117916240-A | Imidazo [1,2-b ] [1,2,4] triazole derivatives for use in therapy | 赛诺菲 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023285466-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZOL DERIVATIVES FOR USE IN THERAPY | SANOFI (FR) | 2023-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300956-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZOL DERIVATIVES FOR USE IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRAS, AADAC | KMT2A 1602/4885HTR6 1777/4885HDAC3 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.