SCHEMBL30183645

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)(C)S

nearest known ligand 0.54

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.54

▸	MAPK9	P45984	1/20	0.54

▸	MAPK10	P53779	1/20	0.54

▸	NTSR1	P30989	5/20	0.50

▸	NTSR2	O95665	4/20	0.50

▸	NPY2R	P49146	8/20	0.49

▸	NPY4R	P50391	8/20	0.49

▸	NPY5R	Q15761	8/20	0.49

▸	NPY1R	P25929	7/20	0.49

▸	SORT1	Q99523	3/20	0.49

▸	EP300	Q09472	1/20	0.48

▸	HIF1A	Q16665	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30870073	0.95	MAPK8 (0.57)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30581282	0.95	MAPK8 (0.57)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30183954	0.95	MAPK8 (0.57)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30870068	0.95	MAPK8 (0.57)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30581315	0.93	MAPK8 (0.57)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30183813	0.93	MAPK8 (0.55)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30183644	0.92	MAPK8 (0.45)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30870075	0.90	MAPK8 (0.59)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30870039	0.90	MAPK8 (0.59)	MAPK8MAPK9MAPK10NTSR1NTSR2
SCHEMBL30183658	0.90	NPY4R (0.44)	MAPK8MAPK9MAPK10NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4380689-A1	ANTIMICROBIAL PEPTIDOMIMETICS	Basilea Pharmaceutica International AG, Allschwil (CH)	2024-06-12	—	—	EP	claimed
WO-2023012319-A1	ANTIMICROBIAL PEPTIDOMIMETICS	SPEXIS AG (CH)	2023-02-09	—	—	WO	claimed