Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896951 | 1.00 | CRBN (0.44) | CRBNALDH1A1LMNABRD4NR3C1 | |
| SCHEMBL18380965 | 0.90 | ALDH1A1 (0.44) | CRBNALDH1A1LMNAPIM1MAOB | |
| SCHEMBL482610 | 0.86 | CRBN (0.46) | CRBNALDH1A1LMNABRD4NR3C1 | |
| SCHEMBL482238 | 0.83 | CRBN (0.44) | CRBNALDH1A1LMNABRD4CYP3A4 | |
| SCHEMBL897104 | 0.83 | ALDH1A1 (0.44) | CRBNALDH1A1LMNABRD4CYP3A4 | |
| SCHEMBL896071 | 0.82 | CRBN (0.46) | CRBNALDH1A1LMNABRD4NR3C1 | |
| SCHEMBL896302 | 0.82 | CRBN (0.62) | CRBNALDH1A1LMNABRD4NR3C1 | |
| SCHEMBL896995 | 0.81 | CRBN (0.52) | CRBNALDH1A1LMNABRD4NR3C1 | |
| SCHEMBL482645 | 0.80 | CRBN (0.46) | CRBNALDH1A1LMNABRD4CYP3A4 | |
| SCHEMBL482629 | 0.80 | CRBN (0.51) | CRBNALDH1A1LMNABRD4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111557899-B | Medicine for treating keratitis and preparation method thereof | 北华大学 | 2023-02-21 | — | — | CN | disclosed |
| CN-111557899-B | Medicine for treating keratitis and preparation method thereof | 北华大学 | 2023-02-21 | — | — | CN | disclosed |