Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578335 | 1.00 | NPSR1 (0.53) | NPSR1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL23577903 | 0.90 | MEN1 (0.44) | NPSR1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL30184001 | 0.90 | MEN1 (0.44) | NPSR1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL2903296 | 0.80 | TDP1 (0.53) | MEN1KMT2ATDP1KDM4EPDGFRB | |
| SCHEMBL1786813 | 0.80 | MEN1 (0.51) | MEN1KMT2ATDP1KDM4EPDGFRB | |
| SCHEMBL23577610 | 0.78 | NPSR1 (0.47) | NPSR1TDP1PDGFRBFGFR1PDGFRA | |
| SCHEMBL23578020 | 0.78 | MEN1 (0.41) | NPSR1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1786384 | 0.77 | TDP1 (0.51) | MEN1KMT2ATDP1KDM4EPDGFRB | |
| SCHEMBL1788077 | 0.77 | PDGFRB (0.55) | NPSR1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL14809433 | 0.76 | MEN1 (0.48) | MEN1KMT2ATDP1KDM4EPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |