Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23590557 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL23591041 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL30184140 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL30035604 | 0.86 | KMT2A (0.46) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL23578010 | 0.86 | KMT2A (0.46) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL23590714 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL30183881 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL23578406 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL23577792 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL23577856 | 0.79 | MAPT (0.36) | ALDH1A1KDM4EHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |