Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577857 | 1.00 | KMT2A (0.56) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL26119918 | 0.92 | KMT2A (0.55) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL30623227 | 0.92 | KMT2A (0.55) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL23578026 | 0.86 | KMT2A (0.50) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL30036547 | 0.84 | KMT2A (0.48) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL23577820 | 0.84 | KMT2A (0.48) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL23577644 | 0.84 | KMT2A (0.48) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL30183966 | 0.84 | KDM4E (0.50) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL23590633 | 0.84 | KDM4E (0.50) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 | |
| SCHEMBL26123056 | 0.82 | KMT2A (0.46) | KMT2AKDM4ENPSR1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |