Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30183966 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL30183958 | 0.84 | KMT2A (0.56) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL23577857 | 0.84 | KMT2A (0.56) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL23578453 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL30183827 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL30623227 | 0.77 | KMT2A (0.55) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL26119918 | 0.77 | KMT2A (0.55) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL23578385 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL71222 | 0.72 | TSHR (0.57) | KDM4EALDH1A1SMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL30036547 | 0.72 | KMT2A (0.48) | KDM4EALDH1A1HPGDKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2021130731-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |