Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | FURIN | P09958 | 5/20 | 0.49 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904521 | 0.87 | EGFR (0.54) | BACE1EGFRFURINPCSK6GRIN2D | |
| SCHEMBL29364756 | 0.86 | NPY1R (0.57) | EGFRFURINPCSK6GRIN2DGRIN3B | |
| SCHEMBL29389069 | 0.85 | BACE1 (0.51) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29973381 | 0.85 | BACE1 (0.51) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29386588 | 0.85 | BACE1 (0.51) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30023295 | 0.84 | EGFR (0.52) | BACE1EGFRFURINPCSK6GRIN2D | |
| SCHEMBL30432819 | 0.84 | BACE1 (0.55) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8983878 | 0.83 | BACE1 (0.54) | BACE1BACE2CTSD | |
| SCHEMBL8983897 | 0.83 | BACE1 (0.54) | BACE1BACE2CTSD | |
| SCHEMBL29711237 | 0.83 | BACE1 (0.49) | BACE1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034551-A1 | METHODS AND SYSTEMS FOR HIGH-THROUGHPUT BIOCHEMICAL SCREENS | NATIONAL SCIENCE FOUNDATION | 2025-01-30 | — | — | US | disclosed |
| US-20240366738-A1 | MOLECULAR VACCINES FOR INFECTIOUS DISEASE | AGILENT TECHNOLOGIES INC (US) | 2024-11-07 | — | — | US | disclosed |
| EP-4426882-A1 | METHODS AND SYSTEMS FOR HIGH-THROUGHPUT BIOCHEMICAL SCREENS | Think Bioscience, Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| US-11992518-B2 | Molecular vaccines for infectious disease | AGILENT TECHNOLOGIES, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| US-20240117017-A1 | HIV VACCINES AND METHODS OF MAKING AND USING | GILEAD SCIENCES, INC. | 2024-04-11 | — | — | US | disclosed |
| US-11795210-B2 | HIV vaccines and methods of making and using | GILEAD SCIENCES, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| WO-2023081783-A1 | METHODS AND SYSTEMS FOR HIGH-THROUGHPUT BIOCHEMICAL SCREENS | THINK BIOSCIENCE, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-4118098-A1 | METHODS AND COMPOSITION FOR GENE DELIVERY USING AN ENGINEERED VIRAL PARTICLE | The Trustees of The University of Pennsylvania (US) | 2023-01-18 | — | — | EP | disclosed |