SCHEMBL30184408

SCHEMBL30184408

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nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 6/20 0.56
▸ KISS1R Q969F8 5/20 0.53
▸ BACE2 Q9Y5Z0 3/20 0.52
▸ OPRM1 P35372 1/20 0.49
▸ OPRD1 P41143 1/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ NPY1R P25929 1/20 0.48
▸ NPY2R P49146 1/20 0.48
▸ NPY4R P50391 1/20 0.48
▸ VIPR1 P32241 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30865079 0.98 BACE1 (0.58) BACE1KISS1RBACE2NPY1RNPY2R
SCHEMBL30184172 0.97 KISS1R (0.53) BACE1KISS1RBACE2OPRM1OPRD1
SCHEMBL31690550 0.97 KISS1R (0.56) BACE1KISS1RBACE2VIPR1
SCHEMBL29678306 0.94 KISS1R (0.56) BACE1KISS1RBACE2VIPR1
SCHEMBL31690551 0.94 KISS1R (0.56) BACE1KISS1RBACE2VIPR1
SCHEMBL30865069 0.94 KISS1R (0.54) BACE1KISS1ROPRM1OPRD1OPRK1
SCHEMBL30712758 0.91 VIPR1 (0.50) BACE1KISS1RBACE2VIPR1
SCHEMBL29627568 0.90 KISS1R (0.54) BACE1KISS1RBACE2VIPR1
SCHEMBL31696338 0.89 BACE1 (0.67) BACE1KISS1RBACE2
SCHEMBL38662087 0.88 BACE1 (0.56) BACE1KISS1RBACE2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes DR. MARY MORRIS & ASSOCIATES, LLC (US) 2026-02-17 — — US disclosed
US-20230018324-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF TYPE 1 DIABETES DR. MARY MORRIS & ASSOCIATES, LLC (US) 2023-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes IAPP, GLP1R, SLC5A1 BACE1 498/4885KISS1R 416/4885BACE2 1115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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