SCHEMBL30184955

SCHEMBL30184955

CC1CC(c2cccc(Cl)c2)(c2nncn2C)C1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 20/20 0.57
CBL P22681 18/20 0.57
CBLC Q9ULV8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184961 0.85 CBLB (0.55) CBLBCBLCBLC
SCHEMBL30598936 0.85 CBLB (0.57) CBLBCBLCBLC
SCHEMBL22850264 0.85 CBLB (0.57) CBLBCBLCBLC
SCHEMBL30184951 0.85 CBLB (0.57) CBLBCBLCBLC
SCHEMBL22849886 0.85 CBLB (0.57) CBLBCBLCBLC
SCHEMBL24661602 0.85 CBLB (0.57) CBLBCBLCBLC
SCHEMBL30184952 0.84 CBLB (0.55) CBLBCBLCBLC
SCHEMBL30792138 0.81 CBLB (0.54) CBLBCBLCBLC
SCHEMBL24821915 0.81 CBLB (0.57) CBLBCBLCBLC
SCHEMBL30792099 0.81 CBLB (0.57) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023036330-A1 TRICYCLIC COMPOUND AS CBL-B INHIBITOR 先声再明医药有限公司 2023-03-16 WO disclosed