Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.62 |
| ▸ | GLP1R | P43220 | 4/20 | 0.60 |
| ▸ | GCGR | P47871 | 3/20 | 0.60 |
| ▸ | CALCR | P30988 | 3/20 | 0.60 |
| ▸ | F2 | P00734 | 4/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
| ▸ | CTSH | P09668 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.57 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276691 | 0.92 | CALCR (0.68) | APLNRGLP1RGCGRCALCRF2 | |
| SCHEMBL31182794 | 0.92 | APLNR (0.64) | APLNRGLP1RGCGRCALCRF2 | |
| SCHEMBL29446772 | 0.92 | CALCR (0.67) | APLNRGLP1RGCGRCALCRF2 | |
| SCHEMBL29963415 | 0.92 | CALCR (0.67) | APLNRGLP1RGCGRCALCRF2 | |
| SCHEMBL30446021 | 0.90 | CALCR (0.68) | APLNRGLP1RGCGRCALCRF2 | |
| SCHEMBL29695502 | 0.90 | APLNR (0.64) | APLNRCALCRF2CTSLCTSS | |
| SCHEMBL30524357 | 0.89 | APLNR (0.67) | APLNRGLP1RGCGRCALCRCTSL | |
| SCHEMBL30176412 | 0.89 | MC4R (0.63) | APLNRCALCRF2NMUR2NMUR1 | |
| SCHEMBL30607310 | 0.89 | CALCR (0.66) | APLNRGLP1RGCGRCALCRF2 | |
| SCHEMBL29742982 | 0.89 | CALCR (0.65) | APLNRGLP1RGCGRCALCRF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461783-B | Podophyllin antagonistic polypeptide and derivative and application thereof | 清华大学深圳国际研究生院 | 2023-02-17 | — | — | CN | disclosed |