Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 2/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24985042 | 1.00 | EIF4E (0.43) | EIF4ETRPV3AGPAT2NOTUMMCL1 | |
| SCHEMBL30185174 | 0.90 | NPSR1 (0.45) | EIF4EAGPAT2MCL1CFTRCYP1A2 | |
| SCHEMBL22366910 | 0.90 | NPSR1 (0.45) | EIF4EAGPAT2MCL1CFTRCYP1A2 | |
| SCHEMBL24985471 | 0.89 | MCL1 (0.44) | AGPAT2MCL1CFTRCYP1A2CYP3A4 | |
| SCHEMBL24986498 | 0.89 | AGPAT2 (0.47) | EIF4EAGPAT2MCL1CFTRCYP1A2 | |
| SCHEMBL24984999 | 0.88 | MPL (0.42) | AGPAT2MCL1CFTRCYP1A2CYP3A4 | |
| SCHEMBL30185292 | 0.87 | AGPAT2 (0.41) | AGPAT2NOTUMMCL1CFTRCYP1A2 | |
| SCHEMBL24985500 | 0.87 | MAPT (0.47) | AGPAT2CFTRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24986504 | 0.87 | AGPAT2 (0.41) | AGPAT2NOTUMMCL1CFTRCYP1A2 | |
| SCHEMBL24985309 | 0.87 | NPSR1 (0.44) | EIF4EAGPAT2NOTUMMCL1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | EIF4E 3624/4885TRPV3 3090/4885AGPAT2 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.