Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580016 | 1.00 | HDAC8 (0.54) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL30185495 | 1.00 | HDAC8 (0.54) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL3109875 | 0.88 | HDAC6 (0.61) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL28580033 | 0.86 | PLAU (0.56) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL28586566 | 0.86 | HDAC6 (0.67) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL30185511 | 0.86 | HDAC6 (0.67) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL30185512 | 0.86 | PLAU (0.56) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL9182305 | 0.84 | PAX8 (0.51) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL1180004 | 0.83 | CD74 (0.54) | HDAC8HDAC6HDAC11PLAUPLG | |
| SCHEMBL6086357 | 0.81 | HDAC6 (0.65) | HDAC8HDAC6HDAC11PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |