SCHEMBL30185519

SCHEMBL30185519

CCS(=O)(=O)c1ccc(Cc2cc3cc(C(N)=O)ccc3n2CCc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30185535 0.92 RORC (0.59) RORC
SCHEMBL30185522 0.87 RORC (0.59) RORC
SCHEMBL30185505 0.85 RORC (0.59) RORC
SCHEMBL19360393 0.81 RORC (0.75) RORC
SCHEMBL30185534 0.81 RORC (0.57) RORC
SCHEMBL30185525 0.80 RORC (0.48) RORC
SCHEMBL18440903 0.80 RORC (0.78) RORC
SCHEMBL20634742 0.78 RORC (0.73) RORC
SCHEMBL21877833 0.78 RORC (0.73) RORC
SCHEMBL30185508 0.77 RORC (0.58) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112759541-B Indole-like derivatives and uses thereof 复旦大学 2023-03-17 CN disclosed