Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568252 | 1.00 | MAPT (0.52) | MAPTLMNAHDAC8HDAC6HDAC11 | |
| SCHEMBL28566459 | 0.87 | PLAU (0.52) | MAPTLMNAHDAC8HDAC6HDAC11 | |
| SCHEMBL30185536 | 0.87 | PLAU (0.52) | MAPTLMNAHDAC8HDAC6HDAC11 | |
| SCHEMBL28565969 | 0.86 | PPARG (0.53) | LMNAPPARGPOLBSMN1; SMN2 | |
| SCHEMBL28565911 | 0.85 | KDM4E (0.47) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL30185506 | 0.85 | KDM4E (0.47) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL28573940 | 0.84 | HDAC8 (0.46) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL3109875 | 0.84 | HDAC6 (0.61) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL28573548 | 0.83 | HSP90AA1 (0.47) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL30185509 | 0.83 | HSP90AA1 (0.47) | HDAC8HDAC6HDAC11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |