Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566459 | 1.00 | PLAU (0.52) | PLAUHDAC8HDAC6HDAC11MEN1 | |
| SCHEMBL5881976 | 0.87 | PLAU (0.57) | PLAUHDAC8HDAC6HDAC11MEN1 | |
| SCHEMBL30185528 | 0.87 | MAPT (0.52) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL28568252 | 0.87 | MAPT (0.52) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL28580014 | 0.87 | HDAC6 (0.52) | PLAUHDAC8HDAC6HDAC11HDAC3 | |
| SCHEMBL30185538 | 0.87 | HDAC6 (0.52) | PLAUHDAC8HDAC6HDAC11HDAC3 | |
| SCHEMBL28566467 | 0.85 | PLAU (0.56) | PLAUHDAC8HDAC6NPC1RAB9A | |
| SCHEMBL3109875 | 0.85 | HDAC6 (0.61) | PLAUHDAC8HDAC6HDAC11HDAC3 | |
| SCHEMBL28565911 | 0.84 | KDM4E (0.47) | HDAC8HDAC6HDAC11HDAC3HDAC1 | |
| SCHEMBL30185506 | 0.84 | KDM4E (0.47) | HDAC8HDAC6HDAC11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |