Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 17/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099561 | 1.00 | PIK3CG (0.46) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL31543990 | 0.82 | PIK3CG (0.46) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL30185572 | 0.80 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL29099594 | 0.80 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL30185571 | 0.73 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL29099524 | 0.73 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL30185555 | 0.72 | PIK3CA (0.57) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL30185575 | 0.72 | PIK3CA (0.57) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL29099542 | 0.72 | PIK3CA (0.57) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL31735456 | 0.72 | BRD4 (0.55) | PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |