⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL1149289 | 1.00 | ALDH1A1 (0.31) | — | |
| SCHEMBL4751424 | 0.95 | — | — | |
| SCHEMBL12418751 | 0.75 | — | — | |
| SCHEMBL20745917 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL8523236 | 0.73 | — | — | |
| SCHEMBL24029402 | 0.72 | — | — | |
| SCHEMBL19334096 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL28121424 | 0.70 | — | — | |
| SCHEMBL12418749 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL18782834 | 0.70 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055694-C | Novel process for the isolation of clavulanic acid and pharmaceutically acceptable salts thereof | LEK TOVARNA FARMACEUTSCKIH IN (SI) | 2000-08-23 | — | — | CN | claimed |
| CN-1143388-A | Novel process for isolation of clavulanic acid and of pharmaceutically acceptable salts | LEK TOVARNA FARMACEVTSKIH (SI) | 1997-02-19 | — | — | CN | claimed |
| US-20230203021-A1 | GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME | LG CHEM, LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| EP-4119555-A1 | GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME | Lg Chem, Ltd. (KR) | 2023-01-18 | — | — | EP | disclosed |
| CN-110799516-A | Azithromycin derivatives containing phosphonium ions as anticancer agents | 来兴泰德基金会 | 2020-02-14 | — | — | CN | disclosed |
| US-20190265250-A1 | METHOD OF GENOME-WIDE DIRECT IDENTIFICATION OF ELECTROPHILE-SENSING TARGETS | CORNELL UNIVERSITY | 2019-08-29 | — | — | US | disclosed |
| EP-2760829-B1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-05-18 | — | — | EP | disclosed |
| US-9249096-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-02 | — | — | US | disclosed |
| EP-2760828-B1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |
| US-9120794-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-09-01 | — | — | US | disclosed |
| US-20150105378-A1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-04-16 | — | — | US | disclosed |
| WO-2013048982-A1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | WO | disclosed |
| US-20100190764-A1 | Novel compounds | GLAXO GROUP LIMITED | 2010-07-29 | — | — | US | disclosed |
| EP-2178823-A1 | SPIRO CYCLOPENTANE COMPOUNDS USEFUL AS ANTAGONISTS OF THE H1-RECEPTOR | Glaxo Group Limited (GB) | 2010-04-28 | — | — | EP | disclosed |
| CN-101548018-A | Process for the production of clavulanic acid | DSM IP ASSETS BV (NL) | 2009-09-30 | — | — | CN | disclosed |
| EP-2083843-A2 | MULTIFUNCTIONAL CARRIERS FOR THE DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF | University of Utah Research Foundation (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2009016084-A1 | SPIRO CYCLOPENTANE COMPOUNDS USEFUL AS ANTAGONISTS OF THE H1-RECEPTOR | GLAXO GROUP LIMITED (GB) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008042686-A2 | MULTIFUNCTIONAL CARRIERS FOR THE DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2008-04-10 | — | — | WO | disclosed |
| CN-1055694-C | Novel process for the isolation of clavulanic acid and pharmaceutically acceptable salts thereof | LEK TOVARNA FARMACEUTSCKIH IN (SI) | 2000-08-23 | — | — | CN | disclosed |
| CN-1143388-A | Novel process for isolation of clavulanic acid and of pharmaceutically acceptable salts | LEK TOVARNA FARMACEVTSKIH (SI) | 1997-02-19 | — | — | CN | disclosed |