Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.63 |
| ▸ | MC5R | P33032 | 2/20 | 0.63 |
| ▸ | MC3R | P41968 | 2/20 | 0.63 |
| ▸ | MC1R | Q01726 | 2/20 | 0.63 |
| ▸ | CXCL8 | P10145 | 10/20 | 0.61 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | NPY4R | P50391 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.57 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.56 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.56 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30186411 | 0.91 | MC4R (0.66) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL30670487 | 0.91 | CXCR4 (0.64) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL16692904 | 0.88 | C5AR1 (0.66) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL29389654 | 0.86 | MC4R (0.67) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL31419719 | 0.86 | NPY1R (0.62) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL29733647 | 0.86 | C5AR1 (0.63) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL31364213 | 0.86 | CXCR4 (0.58) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL31419733 | 0.86 | KISS1R (0.60) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL29993973 | 0.86 | C5AR1 (0.59) | MC4RMC5RMC3RMC1RCXCL8 | |
| SCHEMBL30218939 | 0.85 | CXCR4 (0.65) | MC4RMC5RMC3RMC1RCXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165943-A1 | TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION | CHRYSALIS BIOTHERAPEUTICS, INC. | 2023-06-01 | — | — | US | disclosed |
| EP-4132948-A1 | TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION | Chrysalis Biotherapeutics (US) | 2023-02-15 | — | — | EP | disclosed |