SCHEMBL30186434

C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	6/20	0.44

▸	OPRL1	P41146	2/20	0.43

▸	TFPI	P10646	1/20	0.43

▸	CXCR4	P61073	1/20	0.42

▸	RXFP1	Q9HBX9	1/20	0.42

▸	NPY1R	P25929	2/20	0.41

▸	NPY2R	P49146	2/20	0.41

▸	NPY4R	P50391	2/20	0.41

▸	NPY5R	Q15761	2/20	0.41

▸	KEAP1	Q14145	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30186416	0.95	IL23R (0.44)	IL23ROPRL1TFPICXCR4NPY1R
SCHEMBL31689761	0.93	IL23R (0.42)	IL23ROPRL1NPY1RNPY2RNPY4R
SCHEMBL31676593	0.92	TFPI (0.45)	OPRL1TFPIRXFP1NPY1RNPY2R
SCHEMBL31676591	0.92	TFPI (0.45)	OPRL1TFPIRXFP1NPY1RNPY2R
SCHEMBL31211745	0.91	FOLH1 (0.45)	OPRL1TFPICXCR4NPY1RNPY2R
SCHEMBL29809691	0.90	NPY4R (0.51)	TFPICXCR4RXFP1NPY1RNPY2R
SCHEMBL30433111	0.90	OPRL1 (0.51)	OPRL1TFPIKEAP1
SCHEMBL31277220	0.89	IL23R (0.45)	IL23ROPRL1TFPICXCR4RXFP1
SCHEMBL30140825	0.89	TFPI (0.52)	TFPIRXFP1NPY1RNPY2RNPY4R
SCHEMBL10872838	0.89	TFPI (0.45)	OPRL1TFPICXCR4RXFP1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4132948-A1	TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION	Chrysalis Biotherapeutics (US)	2023-02-15	—	—	EP	disclosed