⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577772 | 1.00 | — | — | |
| SCHEMBL1577558 | 1.00 | — | — | |
| SCHEMBL1888094 | 1.00 | — | — | |
| SCHEMBL1578039 | 1.00 | — | — | |
| SCHEMBL4155993 | 0.77 | GRM4 (0.33) | — | |
| SCHEMBL301120 | 0.77 | — | — | |
| SCHEMBL12473695 | 0.77 | — | — | |
| SCHEMBL21019008 | 0.77 | — | — | |
| SCHEMBL1173556 | 0.77 | — | — | |
| SCHEMBL302705 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115838329-A | Method for synthesizing (1R, 2S) -2-fluoro-cyclopropanecarboxylic acid | 邯郸市瑞田农药有限公司 | 2023-03-24 | — | — | CN | claimed |
| WO-2013007765-A1 | FUSED TRICYCLIC COMPOUNDS FOR USE AS INHIBITORS OF JANUS KINASES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | claimed |
| JP-8268956-A | — | — | None | — | — | JP | disclosed |
| JP-8198804-A | — | — | None | — | — | JP | disclosed |
| EP-4562001-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | Nura Bio, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026368-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-115838329-A | Method for synthesizing (1R, 2S) -2-fluoro-cyclopropanecarboxylic acid | 邯郸市瑞田农药有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115838329-A | Method for synthesizing (1R, 2S) -2-fluoro-cyclopropanecarboxylic acid | 邯郸市瑞田农药有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-112654605-B | Bridged heterocyclic group substituted pyrimidine compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-20220348572-A1 | BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | The National Institutes of Pharmaceutical R&D Co., Ltd. (CN) | 2022-11-03 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-5780669-A | Selective dehalogenation process | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5770767-A | Process for producing 2-fluorocyclopropancecarboxlic acid | SUMITOMO CHEMICAL COMPANY LIMITED. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0436348-B1 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LTD (GB) | 1996-11-13 | — | — | EP | disclosed |
| JP-H08268956-A | PRODUCTION OF 2-FLUOROCYCLOPROPANECARBOXYLIC ACID COMPOUND | SUMITOMO CHEM CO LTD | 1996-10-15 | — | — | JP | disclosed |
| EP-0726244-A1 | Process for producing 2-fluorocyclopropanecarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |
| JP-H08198804-A | PRODUCTION OF 2-FLUOROCYCLOPROPANECARBOXYLIC ACID | DAI ICHI SEIYAKU CO LTD | 1996-08-06 | — | — | JP | disclosed |
| EP-0712831-A1 | SELECTIVE DEHALOGENATION METHOD | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |
| US-5126338-A | FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0436348-A2 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LIMITED (GB) | 1991-07-10 | — | — | EP | disclosed |