⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173556 | 1.00 | — | — | |
| SCHEMBL12473695 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11821301 | 0.97 | — | — | |
| Bromide SCHEMBL11824101 | 0.97 | — | — | |
| Trolamine SCHEMBL30388357 | 0.82 | CHRNB2 (0.35) | — | |
| SCHEMBL22500876 | 0.78 | SLC6A4 (0.38) | — | |
| SCHEMBL22519005 | 0.78 | CHRNB2 (0.36) | — | |
| SCHEMBL22493943 | 0.78 | SLC6A4 (0.38) | — | |
| SCHEMBL28137306 | 0.78 | CHRNB2 (0.41) | — | |
| SCHEMBL28151260 | 0.78 | CHRNB2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490150-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-01-15 | — | — | EP | claimed |
| CN-117964616-A | Synthesis method and application of JAK inhibitor drug compound | 珠海联邦制药股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2023170025-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-09-14 | — | — | WO | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| CN-104900853-B | A kind of synthesis in solid state Co2+Doping fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-09-22 | — | — | CN | claimed |
| CN-104795536-B | A kind of liquid phase synthesis B3+, La3+Orthohormbic structure of adulterating fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104900854-B | A kind of liquid phase synthesis Mn2+Doping fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104795538-B | A kind of oxygen-containing fluorination bismuth anode material for lithium-ion batteries of synthesis in solid state and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104916818-B | A kind of liquid phase synthesis Al3+,Y3+Adulterate cubic structure fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104882602-B | A kind of synthesis in solid state Al3+,Cu2+Adulterate cubic structure fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-15 | — | — | CN | claimed |
| EP-2467368-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-06-27 | — | — | EP | claimed |
| US-20110313151-A1 | ANELLATED PYRIDINE COMPOUNDS | HOFFMANN-LA ROCHE, INC. | 2011-12-22 | — | — | US | claimed |
| US-8039490-B2 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | HOFFMANN-LA ROCHE INC. (US) | 2011-10-18 | — | — | US | claimed |
| US-20090197935-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2009-08-06 | — | — | US | claimed |
| EP-2018371-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-01-28 | — | — | EP | claimed |
| EP-1987019-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS 5HT2/D3 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007136703-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007093540-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS 5HT2/D3 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | claimed |
| US-20070197531-A1 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-08-23 | — | — | US | claimed |
| EP-0300155-A2 | Cyclopropyl amines | BAYER AG (DE) | 1989-01-25 | — | — | EP | claimed |