SCHEMBL30187142

SCHEMBL30187142

COc1ccc(-c2ccc3c(c2)cc(C(=O)O)c(=O)n3CCN2CCOCC2)cc1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.69
CNR1 P21554 3/20 0.54
CREBBP Q92793 1/20 0.49
MMP2 P08253 1/20 0.46
MMP8 P22894 1/20 0.46
MMP12 P39900 1/20 0.46
MMP13 P45452 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24937543 1.00 CNR2 (0.69) CNR2CNR1CREBBPMMP2MMP8
SCHEMBL30187123 0.89 CNR2 (0.65) CNR2CNR1CREBBPMAOAMAOB
SCHEMBL30187121 0.89 CNR2 (0.65) CNR2CNR1CREBBPMAOAMAOB
SCHEMBL24002822 0.89 CNR2 (0.65) CNR2CNR1CREBBPMAOAMAOB
SCHEMBL30187134 0.85 CNR2 (0.73) CNR2CNR1
SCHEMBL24002503 0.85 CNR2 (0.73) CNR2CNR1
SCHEMBL24002572 0.82 CNR2 (1.00) CNR2CNR1
SCHEMBL30305003 0.80 CNR1 (0.57) CNR2CNR1MMP2MMP8MMP12
SCHEMBL4539709 0.78 ALDH1A1 (0.57) CNR2CNR1KDM4EALDH1A1HPGD
SCHEMBL24003002 0.74 CNR1 (0.54) CNR2CNR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835909-B Cannabinoid receptor type 2 (CB 2) modulators and uses thereof 泰昂治疗公司 2026-05-15 CN disclosed
CN-115835909-A Cannabinoid receptor type 2 (CB 2) modulators and uses thereof 泰昂治疗公司 2023-03-21 CN disclosed
EP-4146345-A2 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF Teon Therapeutics, Inc. (US) 2023-03-15 EP disclosed