SCHEMBL30187584

SCHEMBL30187584

COc1cnc2c(-c3nc4c(Cl)cccc4s3)cc(C)cc2n1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395454 1.00 F2RL3 (0.64) F2RL3
SCHEMBL21395654 0.89 F2RL3 (0.67) F2RL3
SCHEMBL30187738 0.88 F2RL3 (0.77) F2RL3
SCHEMBL21395420 0.88 F2RL3 (0.77) F2RL3
SCHEMBL19782987 0.86 F2RL3 (0.53) F2RL3
SCHEMBL30187672 0.86 F2RL3 (0.53) F2RL3
SCHEMBL19783551 0.86 F2RL3 (0.62) F2RL3
SCHEMBL30187595 0.86 F2RL3 (0.62) F2RL3
SCHEMBL21395457 0.85 F2RL3 (0.81) F2RL3
SCHEMBL30187643 0.85 F2RL3 (0.81) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed