SCHEMBL30187672

SCHEMBL30187672

COCc1cnc2c(-c3nc4c(Cl)cccc4s3)cc(C)cc2n1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 13/20 0.53
AGPAT2 O15120 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782987 1.00 F2RL3 (0.53) F2RL3AGPAT2
SCHEMBL19782589 0.89 F2RL3 (0.59) F2RL3AGPAT2
SCHEMBL30187567 0.87 F2RL3 (0.69) F2RL3
SCHEMBL21395449 0.87 F2RL3 (0.56) F2RL3
SCHEMBL30187538 0.87 F2RL3 (0.56) F2RL3
SCHEMBL19782610 0.87 F2RL3 (0.69) F2RL3
SCHEMBL30187584 0.86 F2RL3 (0.64) F2RL3
SCHEMBL21395454 0.86 F2RL3 (0.64) F2RL3
SCHEMBL21395716 0.86 F2RL3 (0.56) F2RL3
SCHEMBL19783479 0.86 F2RL3 (0.51) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed