Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783470 | 1.00 | F2RL3 (0.63) | F2RL3MAOAMAOBTOP2AMAPT | |
| SCHEMBL19783284 | 0.89 | F2RL3 (0.62) | F2RL3MAOAMAOBTOP2ANPC1 | |
| SCHEMBL30189642 | 0.89 | F2RL3 (0.62) | F2RL3MAOAMAOBTOP2ANPC1 | |
| SCHEMBL19783398 | 0.88 | F2RL3 (0.64) | F2RL3MAOAMAOBTOP2ANPC1 | |
| SCHEMBL30187605 | 0.88 | F2RL3 (0.64) | F2RL3MAOAMAOBTOP2ANPC1 | |
| SCHEMBL19783803 | 0.84 | F2RL3 (0.73) | F2RL3MAOAMAOBTOP2AMAPT | |
| SCHEMBL30187691 | 0.84 | F2RL3 (0.73) | F2RL3MAOAMAOBTOP2AMAPT | |
| SCHEMBL19783498 | 0.81 | F2RL3 (0.76) | F2RL3MAOAMAOBNPC1RAB9A | |
| SCHEMBL30187592 | 0.81 | F2RL3 (0.76) | F2RL3MAOAMAOBNPC1RAB9A | |
| SCHEMBL30187685 | 0.80 | F2RL3 (0.62) | F2RL3MAOAMAOBTOP2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |