Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783257 | 1.00 | F2RL3 (0.62) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL19782922 | 0.81 | F2RL3 (0.64) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL30189755 | 0.81 | F2RL3 (0.64) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL19783470 | 0.80 | F2RL3 (0.63) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL19783498 | 0.80 | F2RL3 (0.76) | F2RL3MAOAMAOBKMT2ARAB9A | |
| SCHEMBL30187684 | 0.80 | F2RL3 (0.63) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL30187592 | 0.80 | F2RL3 (0.76) | F2RL3MAOAMAOBKMT2ARAB9A | |
| SCHEMBL19783284 | 0.79 | F2RL3 (0.62) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL30189642 | 0.79 | F2RL3 (0.62) | F2RL3MAOAMAOBTOP2APDE4D | |
| SCHEMBL19783803 | 0.78 | F2RL3 (0.73) | F2RL3MAOAMAOBTOP2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |