Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29301370 | 1.00 | CYP2D6 (0.38) | CYP2D6PARP1 | |
| SCHEMBL30188364 | 1.00 | CYP2D6 (0.38) | CYP2D6PARP1 | |
| SCHEMBL30188428 | 1.00 | CYP2D6 (0.38) | CYP2D6PARP1 | |
| SCHEMBL29301540 | 0.92 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL30189263 | 0.91 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL29301363 | 0.91 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL30189428 | 0.91 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL30188274 | 0.91 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL30188550 | 0.90 | CYP2D6 (0.39) | CYP2D6PARP1 | |
| SCHEMBL30188458 | 0.90 | CYP2D6 (0.39) | CYP2D6PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | claimed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |