Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30188274 | 1.00 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL30189428 | 1.00 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL29301363 | 1.00 | CYP2D6 (0.42) | CYP2D6 | |
| SCHEMBL30188364 | 0.91 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL29301370 | 0.91 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL30188287 | 0.91 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL30188428 | 0.91 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL29301540 | 0.91 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL30189271 | 0.88 | CYP2D6 (0.36) | CYP2D6 | |
| SCHEMBL30188421 | 0.88 | CYP2D6 (0.38) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |