Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348634 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1SCN9ASCN10AHSD17B10 | |
| SCHEMBL3908139 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1SCN9ASCN10AHSD17B10 | |
| SCHEMBL30075375 | 0.83 | NPC1 (0.40) | KDM4EALDH1A1SCN9ASCN10AHSD17B10 | |
| SCHEMBL26352921 | 0.83 | NPC1 (0.40) | KDM4EALDH1A1SCN9ASCN10AHSD17B10 | |
| SCHEMBL31602911 | 0.83 | MEN1 (0.56) | KDM4EALDH1A1HSD17B10TP53KMT2A | |
| SCHEMBL23320971 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL5281382 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1SCN9ASCN10AHSD17B10 | |
| SCHEMBL31439919 | 0.78 | SCN9A (0.46) | SCN9A | |
| SCHEMBL17632197 | 0.77 | NPC1 (0.46) | SCN9AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL30376133 | 0.77 | NPC1 (0.46) | SCN9AKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542273-B2 | Amide compound having bet proteolysis-inducing action and medicinal application thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542273-B2 | Amide compound having bet proteolysis-inducing action and medicinal application thereof | BET1, BRD4, PHKB | KDM4E 261/4885ALDH1A1 4054/4885SCN9A 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.