Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31598280 | 0.78 | HTR2C (0.46) | HSP90AA1HTR2CCHRNB2CHRNA4 | |
| SCHEMBL28508529 | 0.74 | HRH3 (0.40) | HRH3HRH1HTR2CAXL | |
| SCHEMBL30675389 | 0.74 | CHRNB2 (0.44) | CHRNB2CHRNA4 | |
| SCHEMBL29870817 | 0.73 | HTR2C (0.40) | HTR2C | |
| SCHEMBL3389292 | 0.72 | HRH3 (0.58) | HRH3HRH1 | |
| SCHEMBL28949544 | 0.72 | HTR2C (0.51) | HSP90AA1HTR2C | |
| SCHEMBL31598150 | 0.72 | HTR2C (0.46) | HTR2C | |
| SCHEMBL14287582 | 0.69 | HRH3 (0.88) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5093642 | 0.68 | HRH3 (0.86) | HRH3HRH1 | |
| SCHEMBL26639995 | 0.68 | AXL (0.51) | HRH3AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |