Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22886451 | 1.00 | LMNA (0.41) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL30189372 | 0.87 | MAPT (0.44) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL28665696 | 0.84 | SMN1; SMN2 (0.49) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL1144241 | 0.84 | MAPT (0.46) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL20028730 | 0.84 | MAPT (0.47) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL30189419 | 0.84 | MAPT (0.47) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL1144240 | 0.84 | MAPT (0.46) | LMNACYP1A2CYP3A4MAOANPSR1 | |
| SCHEMBL1144606 | 0.83 | MAPT (0.50) | LMNANPSR1RAB9A | |
| SCHEMBL8227037 | 0.83 | MAPT (0.50) | LMNANPSR1RAB9A | |
| SCHEMBL1144604 | 0.83 | MAPT (0.50) | LMNANPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636782-B | Synthesis method of polyaryl substituted pyridine | 浙江工业大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-115636782-A | Synthetic method of polyaryl substituted pyridine | 浙江工业大学 | 2023-01-24 | — | — | CN | disclosed |