SCHEMBL30189447

SCHEMBL30189447

CCC(C)c1cccnc1-c1ncccc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
NISCH Q9Y2I1 1/20 0.36
HTT P42858 1/20 0.35
ALDH1A1 P00352 4/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
NPC1 O15118 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CDC25B P30305 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PDE1A P54750 3/20 0.31
PDE1B Q01064 3/20 0.31
PDE1C Q14123 3/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30189543 0.82 GABRA1 (0.38) TSHRL3MBTL1HPGDCYP1A2NPC1
SCHEMBL23565852 0.79 TSHR (0.47) TSHRNISCHHTTALDH1A1L3MBTL1
SCHEMBL19039496 0.77 TSHR (0.46) TSHRNISCHHTTALDH1A1L3MBTL1
SCHEMBL7772699 0.75 CDC25B (0.46) HTTALDH1A1L3MBTL1CYP1A2CYP2C19
SCHEMBL29666462 0.75 CDC25B (0.46) HTTALDH1A1L3MBTL1CYP1A2CYP2C19
SCHEMBL3708329 0.74 TSHR (0.59) TSHRNISCHHTTALDH1A1L3MBTL1
SCHEMBL29573338 0.74 TSHR (0.59) TSHRNISCHHTTALDH1A1L3MBTL1
SCHEMBL13981277 0.73 TSHR (0.48) TSHRNISCHHTTALDH1A1L3MBTL1
SCHEMBL10134256 0.73 TSHR (0.48) TSHRNISCHHTTALDH1A1L3MBTL1
SCHEMBL19058565 0.73 TSHR (0.48) TSHRNISCHHTTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636890-A Iron catalyst for selective polymerization of conjugated diolefins with 1,2/3,4 and application thereof 宁波大学 2023-01-24 CN disclosed