SCHEMBL301897

SCHEMBL301897

C/C(=C\C(=O)O)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233238 1.00
SCHEMBL301898 1.00
SCHEMBL370991 0.79
SCHEMBL21589352 0.79
SCHEMBL746417 0.79
SCHEMBL3789442 0.79
SCHEMBL370990 0.79
SCHEMBL18528362 0.78
SCHEMBL17234255 0.78
SCHEMBL5703610 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10166527-B2 Surface modification of porous base supports MERCK PATENT GMBH (DE) 2019-01-01 US claimed
WO-2017161206-A1 CONJUGATES CONTAINING CONDITIONALLY ACTIVE ANTIBODIES OR ANTIGEN-BINDING FRAGMENTS THEREOF, AND METHODS OF USE HALOZYME, INC. (US) 2017-09-21 WO claimed
US-20150298097-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2015-10-22 US claimed
EP-2914377-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS Merck Patent GmbH (DE) 2015-09-09 EP claimed
WO-2014067605-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2014-05-08 WO claimed
EP-4060101-B1 CARBON FIBER AND METHOD FOR PRODUCING THE SAME TOYOTA CHUO KENKYUSHO KK (JP) 2026-02-18 EP disclosed
EP-4205203-B1 2,5-DIMERCAPTO-1,3,4-THIADIAZOLE (\"DMTD\") METAL SALT DERIVATIVES LUBRIZOL CORP (US) 2025-08-06 EP disclosed
WO-2025119748-A1 CYCLOHEXYL-SUBSTITUTED 4-HYDROXY-PYRAZOLE POLYMERIZATION INHIBITORS BASF SE (DE) 2025-06-12 WO disclosed
WO-2025119744-A1 PHENYL-SUBSTITUTED 4-HYDROXY-PYRAZOLE POLYMERIZATION INHIBITORS BASF SE (DE) 2025-06-12 WO disclosed
US-12291510-B2 2,5-dimercapto-1,3,4-thiadiazole (DMTD) derivatives THE LUBRIZOL CORPORATION (US) 2025-05-06 US disclosed
US-12163258-B2 Carbon fiber and method for producing the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2024-12-10 US disclosed
EP-3500595-B1 ANTI-PSMA ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF ABZENA UK LTD (GB) 2024-05-01 EP disclosed
US-20090298154-A1 Conjugated biological molecules and their preparation POLYTHERICS LIMITED (GB) 2009-12-03 US disclosed
US-7595292-B2 Conjugated biological molecules and their preparation POLYTHERICS LIMITED (GB) 2009-09-29 US disclosed
EP-1648518-B1 CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION POLYTHERICS LTD (GB) 2009-08-26 EP disclosed
WO-2009047500-A1 NOVEL CONJUGATED PROTEINS AND PEPTIDES POLYTHERICS LIMITED (GB) 2009-04-16 WO disclosed
US-20060210526-A1 polyoxyethylene glycol-protein conjugate linked via linking group ABZENA (CAMBRIDGE) LIMITED (GB) 2006-09-21 US disclosed
EP-1648518-A2 CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION Polytherics Limited (GB) 2006-04-26 EP disclosed
WO-2005007197-A2 CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION POLYTHERICS LIMITED (GB) 2005-01-27 WO disclosed
WO-2003033028-A2 MULTIMERIC PROTEINS UNIVERSITY OF SOUTHAMPTON (GB) 2003-04-24 WO disclosed