Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783059 | 1.00 | HSD17B10 (0.37) | HSD17B10IKBKBMAPTF2RL3NPC1 | |
| SCHEMBL23462902 | 0.85 | HSD17B10 (0.55) | HSD17B10IKBKBMAPTHTTRAB9A | |
| SCHEMBL30189658 | 0.84 | KMT2A (0.40) | HSD17B10IKBKBMAPTF2RL3KDM4E | |
| SCHEMBL19782545 | 0.84 | KMT2A (0.40) | HSD17B10IKBKBMAPTF2RL3KDM4E | |
| SCHEMBL19783647 | 0.83 | MAPT (0.44) | HSD17B10MAPTNPC1HTTRAB9A | |
| SCHEMBL11102832 | 0.82 | LMNA (0.43) | HSD17B10IKBKBMAPTF2RL3NPC1 | |
| SCHEMBL21379500 | 0.81 | GAA (0.35) | HSD17B10IKBKBMAPTHTTLMNA | |
| SCHEMBL19782939 | 0.78 | F2RL3 (0.43) | HSD17B10MAPTF2RL3NPC1RAB9A | |
| SCHEMBL19782752 | 0.74 | GAA (0.48) | HSD17B10MAPTHTTKDM4EHPGD | |
| SCHEMBL30189687 | 0.73 | IKBKB (0.53) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |