SCHEMBL30189757

SCHEMBL30189757

COc1cnc2c(-c3nc4c(C(=O)C(C)(C)C)cc(O)cc4s3)cc(C)cc2n1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783638 1.00 F2RL3 (0.50) F2RL3
SCHEMBL30189998 0.89 F2RL3 (0.61) F2RL3
SCHEMBL19782698 0.89 F2RL3 (0.61) F2RL3
SCHEMBL19783072 0.87 F2RL3 (0.52) F2RL3
SCHEMBL30189796 0.87 F2RL3 (0.52) F2RL3
SCHEMBL19783159 0.85 F2RL3 (0.63) F2RL3
SCHEMBL19783347 0.79 F2RL3 (0.61) F2RL3
SCHEMBL30187519 0.79 F2RL3 (0.61) F2RL3
SCHEMBL19782677 0.76 F2RL3 (0.62) F2RL3
SCHEMBL30187587 0.76 F2RL3 (0.62) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed