SCHEMBL30189796

SCHEMBL30189796

CCOc1cc(C(=O)C(C)(C)C)c2nc(-c3cc(C)cc4nc(OC)cnc34)sc2c1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783072 1.00 F2RL3 (0.52) F2RL3
SCHEMBL19783638 0.87 F2RL3 (0.50) F2RL3
SCHEMBL30189757 0.87 F2RL3 (0.50) F2RL3
SCHEMBL30187602 0.83 F2RL3 (0.54) F2RL3
SCHEMBL19783599 0.83 F2RL3 (0.54) F2RL3
SCHEMBL30187519 0.82 F2RL3 (0.61) F2RL3
SCHEMBL19783347 0.82 F2RL3 (0.61) F2RL3
SCHEMBL28941167 0.80 F2RL3 (0.60) F2RL3
SCHEMBL19782809 0.79 F2RL3 (0.64) F2RL3
SCHEMBL30189575 0.78 F2RL3 (0.63) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed