Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783530 | 1.00 | LMNA (0.33) | LMNAKDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL28383665 | 0.82 | GAA (0.35) | LMNAKDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL19782603 | 0.79 | HSD17B10 (0.49) | LMNACYP3A4HSD17B10ADORA3 | |
| SCHEMBL30189823 | 0.79 | HSD17B10 (0.49) | LMNACYP3A4HSD17B10ADORA3 | |
| SCHEMBL30189475 | 0.74 | RECQL (0.38) | LMNAKDM4ENQO2 | |
| SCHEMBL19783074 | 0.74 | RECQL (0.38) | LMNAKDM4ENQO2 | |
| SCHEMBL25250290 | 0.73 | AR (0.30) | — | |
| SCHEMBL22392824 | 0.72 | MAPT (0.40) | KDM4EADORA3 | |
| SCHEMBL1129623 | 0.69 | LMNA (0.44) | LMNAKDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL22392806 | 0.68 | BACE1 (0.51) | LMNAKDM4EHSD17B10NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |