Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379626 | 1.00 | MAPT (0.54) | MAPTLMNAL3MBTL1RAB9AKDM4E | |
| SCHEMBL9111469 | 0.77 | KCNJ1 (0.58) | MAPTL3MBTL1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9110821 | 0.77 | KDM4E (0.54) | MAPTLMNAKDM4ECYP1A2CYP2C19 | |
| SCHEMBL25413821 | 0.76 | KDM5A (0.45) | MAPTL3MBTL1RAB9AKDM4ECYP1A2 | |
| SCHEMBL25413782 | 0.76 | MAPT (0.38) | MAPTL3MBTL1RAB9AKDM4ECYP1A2 | |
| SCHEMBL24668346 | 0.76 | MAPT (0.64) | MAPTLMNAKDM4EALDH1A1RXFP1 | |
| SCHEMBL9108667 | 0.75 | MAPT (0.39) | MAPTL3MBTL1RAB9AKDM4ECYP1A2 | |
| SCHEMBL17720574 | 0.74 | LMNA (0.50) | MAPTLMNARAB9AKMT2ATP53 | |
| SCHEMBL25415330 | 0.73 | KDM4E (0.38) | MAPTL3MBTL1RAB9AKDM4ECYP1A2 | |
| SCHEMBL25414626 | 0.72 | KMT2A (0.37) | MAPTLMNAL3MBTL1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |