Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP9X | Q93008 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 2/20 | 0.31 |
| ▸ | CTSE | P14091 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783135 | 1.00 | CYP3A4 (0.39) | CYP3A4CYP1A2CYP2C19MAPTTDP1 | |
| SCHEMBL21396119 | 0.87 | ALDH1A1 (0.36) | NPC1RAB9AALDH1A1KMT2AUSP9X | |
| SCHEMBL30189887 | 0.87 | ALDH1A1 (0.36) | NPC1RAB9AALDH1A1KMT2AUSP9X | |
| SCHEMBL19782902 | 0.78 | NPC1 (0.33) | CYP3A4CYP1A2CYP2C19MAPTTDP1 | |
| SCHEMBL19783590 | 0.76 | NPC1 (0.35) | MAPTTDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL19783149 | 0.75 | NPC1 (0.39) | MAPTNPC1RAB9AKMT2A | |
| SCHEMBL19782709 | 0.75 | F2RL3 (0.56) | — | |
| SCHEMBL30187531 | 0.75 | F2RL3 (0.56) | — | |
| SCHEMBL21379356 | 0.73 | CYP3A4 (0.41) | CYP3A4CYP1A2CYP2C19MAPTTDP1 | |
| SCHEMBL21379367 | 0.71 | CYP3A4 (0.44) | CYP3A4CYP1A2CYP2C19MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |