Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.36 |
| ▸ | ECE1 | P42892 | 3/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630501 | 0.96 | BACE1 (0.34) | BACE1ECE1MME | |
| SCHEMBL29373629 | 0.94 | ECE1 (0.39) | BACE1ECE1MMEITGB2ICAM1 | |
| SCHEMBL31707374 | 0.93 | MME (0.38) | BACE1ECE1MMEITGB2ICAM1 | |
| SCHEMBL31073533 | 0.93 | PDCD1LG2 (0.39) | BACE1ECE1MMEITGB2ICAM1 | |
| SCHEMBL29510840 | 0.92 | MME (0.38) | BACE1MMECTSD | |
| SCHEMBL31474495 | 0.92 | BACE1 (0.33) | BACE1ECE1MME | |
| SCHEMBL29383357 | 0.92 | ECE1 (0.34) | ECE1MME | |
| SCHEMBL30822978 | 0.92 | SLC15A2 (0.35) | MME | |
| SCHEMBL10856404 | 0.92 | SLC15A2 (0.35) | MME | |
| SCHEMBL30712894 | 0.92 | SLC15A2 (0.35) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090356-A2 | MODIFIED MAMMALIAN CELLS FOR IMPROVED PRODUCTION | GENZYME CORPORATION (US) | 2026-04-30 | — | — | WO | disclosed |
| US-20250295796-A1 | CELL PENETRATING POLYPEPTIDES (CPPS) AND THEIR USE IN HUMAN THERAPY | PAGS CO., LTD. (KR) | 2025-09-25 | — | — | US | disclosed |
| EP-4514972-A1 | PROTECTING OLIGONUCLEOTIDES FOR CRISPR GUIDE RNA | University Of Massachusetts (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-119563023-A | Protective oligonucleotides for CRISPR guide RNA | 马萨诸塞大学 | 2025-03-04 | — | — | CN | disclosed |
| US-20240352499-A1 | POLYNUCLEOTIDES ENCODING NOVEL NUCLEASES, COMPOSITIONS THEREOF AND METHODS THEREOF FOR ELIMINATING DNA FROM PROTEIN PREPARATIONS | DANISCO US INC (US) | 2024-10-24 | — | — | US | disclosed |
| EP-4448556-A1 | CELL PENETRATING POLYPEPTIDES (CPPS) AND THEIR USE IN HUMAN THERAPY | RDP Pharma AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-118786136-A | Cell Penetrating Polypeptide (CPP) and its use in human therapy | RDP制药股份公司 | 2024-10-15 | — | — | CN | disclosed |
| EP-4388077-A1 | POLYNUCLEOTIDES ENCODING NOVEL NUCLEASES, COMPOSITIONS THEREOF AND METHODS THEREOF FOR ELIMINATING DNA FROM PROTEIN PREPARATIONS | Danisco US Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-118240856-A | Escherichia coli toxic protein and application and prokaryotic expression method thereof | 中国人民解放军陆军军医大学第二附属医院 | 2024-06-25 | — | — | CN | disclosed |
| CN-117881772-A | Polynucleotides encoding novel nucleases, compositions thereof and methods for eliminating DNA from protein preparations | 丹尼斯科美国公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20240043877-A1 | COMPOSITIONS AND METHODS FOR GENETIC MANIPULATION OF METHANOTROPHS | AQUA-SPARK CALYSTA LLC (NL) | 2024-02-08 | — | — | US | disclosed |
| US-20230407295-A1 | PROTECTING OLIGONUCLEOTIDES FOR CRISPR GUIDE RNA | UNIV MASSACHUSETTS (US) | 2023-12-21 | — | — | US | disclosed |
| WO-2023212327-A1 | PROTECTING OLIGONUCLEOTIDES FOR CRISPR GUIDE RNA | UNIVERSITY OF MASSACHUSETTS (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023111213-A1 | CELL PENETRATING POLYPEPTIDES (CPPS) AND THEIR USE IN HUMAN THERAPY | RDP PHARMA AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| CN-115956120-A | Modified guide RNAs for CRISPR genome editing | 马萨诸塞大学 | 2023-04-11 | — | — | CN | disclosed |
| EP-4150091-A2 | MODIFIED GUIDE RNAS FOR CRISPR GENOME EDITING | University Of Massachusetts (US) | 2023-03-22 | — | — | EP | disclosed |
| WO-2023023644-A1 | POLYNUCLEOTIDES ENCODING NOVEL NUCLEASES, COMPOSITIONS THEREOF AND METHODS THEREOF FOR ELIMINATING DNA FROM PROTEIN PREPARATIONS | DANISCO US INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| US-20220356484-A1 | GENETIC MODIFICATION OF PLANTS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-11-10 | — | — | US | disclosed |